Colts’ fans, while our attention will be turned to Lucas Oil Stadium tomorrow for the game with the Niners, the rest of the AFC South will be in action in other parts of the country.
Let’s take a look at how those teams could fare this week:
1:00 PM ET (CBS): Houston Texans at Buffalo Bills
The Texans are second in the AFC South right now, and will be heading to Indy next weekend. And while the Bills are atrocious, this one won’t be easy for the Texans. This is the kind of game the Bills have to win, and they’ve sort [...]

We’re getting closer and closer to game day in Indianapolis, as the Colts look to keep their undefeated season alive when they take on the 49ers. There’s a lot of different areas that could effect the outcome of this one, so let’s take a look at some key things for the Colts, and figure out who has the advantage in this one.
HOW THE COLTS CAN WIN
The Colts need to keep doing what they’re doing. That might sound a little cliche, but it has worked for them so far this season. Peyton Manning is playing some of the best football of [...]

Probably not the best news coming out of Indianapolis the last day or so, as the Indy Star is reporting that Donald Brown is unlikely to play this week against the Niners.
As for Reggie Wayne, though there hasn’t been anything said that would rule him out for the game this week, that groin injury has to be somewhat of a concern.
Even though he’s missed some practice this week, I would think that Wayne will probably give it a go on Sunday. It definitely hurts not to have Brown in the backfield though, as he’s shown some explosiveness the past [...]

Indy fans, it’s time to turn our attention to this week’s game against the San Francisco 49ers. The Colts are heading into this one red hot, after the 42-6 spanking of the Rams this past Sunday, and look to be firing on all cylinders right now.
As for the Niners, they’ve hit a rough stretch the past few weeks, after starting the season 3-1. But you can bet that they’ll be ready when they roll into Lucas Oil Stadium this weekend, so let’s take a look at some things that you need to know about this week’s opponent.
Record: 3-3
Last Game: L [...]